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Eisai, Merck’s Drug Combo Approved for Advanced Endometrial Cancer

LENVIMA plus KEYTRUDA demonstrates improvements in overall survival, reducing the risk of death by 32%, and progression-free survival by 40%.

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By: Kristin Brooks

Managing Editor, Contract Pharma

Eisai Co. and Merck received approval from the FDA for the combination of Eisai’s LENVIMA, an orally available multiple receptor tyrosine kinase inhibitor, plus Merck’s KEYTRUDA, an anti-PD-1 therapy, for the treatment of advanced endometrial carcinoma that’s not microsatellite instability-high (MSI-H) or mismatch repair deficient (dMMR), who have disease progression following prior systemic therapy.   The approval is based on results from a Phase 3 Study in which LENVIMA plus KEYTRUDA demonst...

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